Complement-Mediated Vasoconstriction and Graft Rejection
نویسندگان
چکیده
منابع مشابه
Complement-mediated vasoconstriction and graft rejection.
The hyperacute rejection of renal allografts has much in common with pigto-dog renal xenograft rejections. An analysis of the xenograft model revealed new functional aspects of graft rejection that appear to be an integral part of the humoral immune injury. Anaphylatoxin or C5a, a cleavage product of the fifth complement component was shown to play a major role in the rejection of isolated kidn...
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Graft rejection frequencies in a population of the sponge Ectyoplasia ferox are reported in relation ta the complexity of the histocompatibility system in this species. The frequency of graft acceptance is high but we show that, despite assumptions in the literature to the contrary, this does not imply that sponges accepting each other’s grafts are genetically identical. This paper reports that...
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Transplantation of solid organs is the treatment of choice for most patients with end-stage organ diseases. In the absence of pharmacological immunosuppression, recognition of foreign (allogeneic) histocompatibility proteins expressedondonorcellsby therecipient’s immunesystem results in rejection of the transplanted tissue(s). One-year renal transplant survival is now routinely over 90% in most...
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Penetrating corneal homografts were performed in rabbits for the purpose of making, surface studies ivith the scanning electron microscope at various stages of rejection. The rejection of graft epithelium was characterized by a disruption and breakdown of its normal structure in an area 60 to 80 nm. in width. Desquamated cells, pits, and craters were observed in the area of rejection which move...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 1972
ISSN: 0009-7330,1524-4571
DOI: 10.1161/01.res.30.3.332